Blood and urine metal ion levels in young and active patients after Birmingham hip resurfacing arthroplasty
FOUR-YEAR RESULTS OF A PROSPECTIVE LONGITUDINAL STUDYJ. Daniel, FRCS, Director of Research1; H. Ziaee, BSc(Hons), Biomedical Scientist1; C. Pradhan, FRCS, Staff Orthopaedic Surgeon1; P. B. Pynsent, PhD, Director2; and D. J. W. McMinn, FRCS, Consultant Orthopaedic Surgeon1 1 The McMinn Centre, 25 Highfield Road, Edgbaston, Birmingham B15 3DP, UK. 2 Research and Teaching Centre, Royal Orthopaedic Hospital, Northfield, Birmingham B31 2AP, UK.
This is a longitudinal study of the daily urinary output and the concentrations in whole blood of cobalt and chromium in patients with metal-on-metal resurfacings over a period of four years……The effects of systemic metal ion exposure in patients with metal-on-metal resurfacing arthroplasties continue to be a matter of concern. The levels in this study provide a baseline against which the in vivo wear performance of newer bearings can be compared.